75 96
Bladder
Cancer
Prognostic Model
for
Predicting
Survival
in
Patients with Disease
Recurrence
Following
Radical
Cystectomy
Luis
A.
Kluth
a , b , y,
Evanguelos
Xylinas
a , c , y, Malte
Rieken
a , d ,Matthew
Kent
e ,Masaomi
Ikeda
f ,Kazumasa Matsumoto
f ,Masayuki Hagiwara
g ,Eiji Kikuchi
g ,Megan
T.
Bing
h ,Amit
Gupta
h ,Joseph M.
Sewell
i ,Badrinath
R. Konety
i ,Tilman
Todenho¨fer
j ,Christian
Schwentner
j ,Alexandra Masson-Lecomte
k ,Dimitri
Vordos
k ,Florian
Roghmann
l ,Joachim Noldus
l ,Aria
A.
Razmaria
m ,Norm D.
Smith
m ,Evi
Comploj
n ,Armin
Pycha
n ,Michael
Rink
b ,Jack
Baniel
o ,Roy Mano
o ,Giacomo Novara
p ,Atiqullah
Aziz
q ,Hans-Martin
Fritsche
q ,Antonin
Brisuda
r ,Trinity
Bivalacqua
s ,Paolo
Gontero
t ,Stephen
A.
Boorjian
u ,Andrew
J.
Vickers
e ,Shahrokh
F.
Shariat
a , v , w , *a
Department
of Urology, Weill
Cornell Medical
College, New
York
Presbyterian Hospital, New
York, NY, USA;
b
Department
of Urology, University Medical-
Center
Hamburg-Eppendorf,
Hamburg,
Germany;
c
Department
of
Urology,
Cochin
Hospital,
Assistance
Publique-Hoˆpitaux
de
Paris,
Paris
Descartes
University,
Paris,
France;
d
Department
of Urology, University Hospital
Basel,
Basel,
Switzerland;
e
Department
of
Epidemiology
and
Biostatistics, Memorial
Sloan-Kettering
Cancer
Center,
New
York,
NY,
USA;
f
Department
of
Urology,
Kitasato
University
School
of Medicine, Minami-ku,
Sagamihara,
Kanagawa,
Japan;
g
Department
of Urology,
Keio University
School
of Medicine,
Shinjuku-ku,
Tokyo,
Japan;
h
Department
of Urology, University
of
Iowa Hospitals
and
Clinics,
Iowa
City,
IA, USA;
i
Department
of Urology, University
of Minnesota
School
of Medicine, Minneapolis, MN, USA;
j
Department
of Urology, University
Medical Hospital
of
Tuebingen,
Tuebingen, Germany;
k
Department
of Urology, Hoˆpital Henri Mondor
Cre´teil,
Cre´teil,
France;
l
Department
of Urology,
Ruhr
University
Bochum, Marienhospital, Herne, Germany;
m
Department
of
Surgery,
Section
of Urology, University
of
Chicago Medicine
and
Biological
Sciences,
Chicago,
IL, USA;
n
Department
of Urology,
General Hospital
of
Bolzano,
Bolzano,
Italy;
o
Department
of Urology,
Rabin Medical
Center,
Petah-Tikva,
Israel;
p
Department
of
Surgical, Oncological
and Gastroenterologic
Sciences, Urology
Clinic, University
of
Padua,
Padua,
Italy;
q
Department
of Urology,
Caritas
St.
Josef Medical
Centre, University
of
Regensburg,
Regensburg, Germany;
r
Department
of Urology,
2nd
Faculty
of Medicine, Hospital Motol,
Charles University
of Praha, Praha, Czech Republic;
s
Department of Urology, The
James Buchanan Brady Urological
Institute,
Johns Hopkins Medical
Institutions, Baltimore, MD,
USA;
t
Department
of Urology, Molinette University Hospital,
Torino,
Italy;
u
Department
of Urology, Mayo Medical
School
and Mayo
Clinic,
Rochester, MN,
USA;
v
Division
of Medical Oncology, Weill
Cornell Medical
College, New
York
Presbyterian Hospital, New
York, NY, USA;
w
Department
of Urology, Medical
University
of
Vienna,
Vienna,
Austria
E U R O P E A N U R O L O G Y F O C U S 1 ( 2 0 1 5 ) 7 5 – 8 1ava il abl e
at
www.sc iencedirect.comjourna l
homepage:
www.europeanurology.comArticle
info
Article
history:
Accepted October
21,
2014
Associate
Editor
Alberto
Briganti
Keywords:
Urothelial
carcinoma
of
the
bladder
Abstract
Background:
Although
the natural history of urothelial
carcinoma of
the bladder
(UCB)
from
radical
cystectomy
(RC)
to
disease
recurrence
(DR)
has
been
investigated
inten-
sively,
the
course of patients who have experienced DR after RC
for UCB
remains poorly
understood.
Objective:
To
evaluate
the
prognostic
value
of
the
Bajorin
criteria
that
consists
of
two
risk
factors: Karnofsky performance status
(KPS) and
the presence of visceral metastases
(VMs)
in
patients with DR
after RC
for UCB.
Furthermore,
to
identify
additional
factors
associated with cancer-specific mortality
(CSM) and
thus build a multivariable model
to
predict
survival
after DR.
y
Contributed
equally.
* Corresponding
author. Department
of Urology, Medical University
of Vienna, Wa¨hringer Gu¨ rtel
18-20,
1090 Vienna, Austria.
Tel.
+43
1
404
00
2616;
Fax:
+43
1
404
002332.
address:
sfshariat@gmail.com(S.F.
Shariat).
http://dx.doi.org/10.1016/j.euf.2014.10.0032405-4569/
#
2015
European
Association
of Urology.
Published
by
Elsevier
B.V.
All
rights
reserved.