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Statistical

analysis:

Fossati,

Sjoberg,

Vickers.

Obtaining

funding:

None.

Administrative,

technical,

or material

support:

None.

Supervision:

Montorsi, Guazzoni.

Other:

None.

Financial disclosures:

Nicola Fossati

certifies

that all conflicts of

interest,

including

specific

financial

interests

and

relationships

and

affiliations

relevant

to

the

subject matter

or materials discussed

in

the manuscript

(eg, employment/affiliation, grants or

funding,

consultancies, honoraria,

stock ownership or options, expert

testimony,

royalties, or patents filed,

received,

or

pending),

are

the

following: None.

Funding/Support

and

role

of

the

sponsor:

None.

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