including
the United
Kingdom
[53]. High
smoking-related
morbidity
and mortality
are
expected
for
at
least
several
decades more
in
the European countries
that now have high
smoking
prevalence.
3.2.5.
Oceania
Two
of
the wealthiest
countries
in
Oceania,
Australia
and
New
Zealand,
have
been
quite
successful
in
reducing
smoking
prevalence
in
both men
and women,
from
>
30%
in
the 1980s
to
<
18%
in 2013
in men and women combined
[15,54].
However,
similar
to
the
smoking
pattern
in
Southeast Asia,
the male
smoking prevalence
in most
other
countries
on
this
continent
(eg,
Papua–New
Guinea
and
Tonga)
is high
( Table 1).
3.3.
Blond
and
black
(dark)
tobacco
Blond
tobacco
is
flue-cured
tobacco
that
is
high
in
sugar
and
produces
a milder, more
inhalable
smoke
compared
with
black
(dark)
tobacco.
More
than
90%
of
cigarettes
smoked
globally
in
2013
were
Virginia
or
American
blended
cigarettes
[55] ,both
of which
are
blond
tobacco.
Black
tobacco
is
chiefly
smoked
in
Latin
America,
Spain,
and
France
[56]and
is
processed with
open-air
curing
or
air
curing
in
barns with
no
or
limited
artificial
heat.
The
strong
varieties
are
usually
used
to
make
cigars,
while
light
varieties
are
used
in
some
cigarette
blends
in
the
countries
above. With
blond
tobacco
being more
popular
among
smokers
globally,
black
tobacco
use
is
decreasing
[57].
For
example,
the
share
of
black
tobacco
in
the
tobacco market
in
Peru
decreased
from
17.6%
in
2000
to
1.5%
in
2009;
the
respective
decrease
in
Spain was
from
23.5%
to
9.2%
[57] .The
few
laboratory
studies
that
exist
on
potentially
carcinogenic
compounds
in
black
and
blond
tobacco
and
their
effects
on
the
human
body
have
shown
higher
concentrations
of
N-nitrosamine
and
2-napthylamine
in
black tobacco and higher urine mutagenicity and blood DNA
adduct
levels
in
black
tobacco
smokers
[56,58].
However,
the
clinical
significance
of
these
differences
is
unclear.
3.4.
Tobacco
products
other
than
cigarettes
Cigarettes
are
the most
common
smoking
product world-
wide.
However,
there
are
other
tobacco
products
that
are
relatively
commonly used
in
some populations. Water pipe
(hookah)
smoking
has
traditionally
been
common
in
the
Middle East and North Africa and
in some parts of Southeast
Asia
[59].
Water
pipe
use
has
increased
among
young
people,
particularly
college
students,
in
Europe
and North
America
[59,60].
In
the United States,
for example, 7–20% of
college
students
[61]and 5.4%
of high
school
students
[62]reported
past-year/current water
pipe
use.
The
use
of
bidi
(tobacco
flakes wrapped
in
a
leaf
of
the
tendu
or
temburni
tree),
a
relatively
inexpensive
tobacco
product,
is
common
in
South
Asia,
in
particular
in
low-income
groups
[5] .In
India,
bidi
is
the most
commonly
used
smoking
product
(prevalence:
9.2%),
followed
by
cigarettes
(5.7%),
water
pipes
(0.9%),
and
other
products
(1%)
[5] .Global
consumption
of
roll-your-own
(RYO)
tobacco
increased
by
45%
from
2000
to
2013,
with
approximately
101
billion
RYO
cigarettes
smoked
worldwide
in
2013
(compared with nearly 6
trillion
regular cigarettes). Approxi-
mately
86%
of
RYO
cigarettes were
smoked
in
the
European
Union, where RYO cigarettes were much cheaper
than regular
cigarettes
[63] .Global
consumption of
cigars and
cigarillos
(a
cigarillo
is
a
smaller,
narrower
version
of
a
cigar)
has
not
changed
since
the
late 2000s
and
is
approximately 24 billion
per
year,
nearly
half
of
which
are
smoked
in
the
United
States
[63] .All
smoking
tobacco products
are
included
in
the
smoking
rates
shown
in
this
article, unless
stated
otherwise.
Smokeless
tobacco use
is
common
in South Asia, Central
Asia,
the
Nordic
countries,
and
Africa
(Supplementary
Table
1).
For
example,
smokeless
tobacco
use
in
India
is
more
common
than
smoking:
32.9%
of
men
and
18.4%
women
are
smokeless
tobacco
users
[5].
Among
children
aged
13–15
yr
in
South Asia, Central Asia,
the Middle
East,
and Africa,
the use of
tobacco products other
than cigarettes
is more
common
than
cigarette
smoking
[5].
3.5.
E-cigarettes
3.5.1.
What
is
an
e-cigarette?
Electronic
cigarettes
(e-cigarettes),
also
called
electronic
nicotine
delivery
systems
(ENDS)
,
are
battery-powered
devices
that
vaporize
a
liquid
solution
called
e-liquid
using
a
heating
element
known
as
an
atomizer
[64] .E-liquid
generally
contains
nicotine,
propylene
glycol,
vegetable
glycerin,
and
various
additives
[64].
E-cigarette
smokers
inhale
the
resulting
aerosol,
which
some
say
gives
the
feeling of cigarette smoking. E-cigarettes are produced with
various
features
(eg, nonrefillable or
refillable), but many of
these
products
resemble
cigarettes.
As
e-cigarettes
do
not
include
combustion,
their
potential
to
deliver
nicotine
to
users
in
a
safer way
than
regular
cigarettes
and
to
aid
tobacco
smokers
in
quitting
are of high
interest; however, significantlymore research
is
necessary
to
evaluate
this potential
rigorously. While
two
randomized
controlled
clinical
trials
have
shown modest
effectiveness
of
e-cigarettes
in
helping
smokers
to
quit
[65,66],
two
longitudinal epidemiological
studies have not
shown
such
a
benefit
at
the
population
level
[64]or
in
cancer patients
[67].
In addition
to research on e-cigarettes
as a smoking cessation
tool,
there
is a crucial need
for more
analysis
on
the
long-term health
effects
of
e-cigarette use
[64],
particularly
because
propylene
glycol
and
other
compounds
in
e-liquids may
expose
e-cigarette
users
to
increased
levels of
toxic chemicals
[68,69]. Also, nicotine
is
an
addictive
substance,
and
e-cigarette
initiation
by
nonsmokers
may
eventually
lead
to
their
taking
up
traditional
cigarettes
[70] .For
these
reasons,
regulations
have
been
recommended
by
some
health
authorities
to
reduce
the
initiation of e-cigarette smoking
in nonsmokers
(see
section
3.7,
Regulating
e-cigarettes
).
3.5.2.
Prevalence
of
use
As
e-cigarettes
have
been
marketed
only
recently,
their
prevalence
of
use
is
generally much
lower
than
cigarette
E U R O P E A N
U R O L O G Y
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1
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